16611022
This study provides the following main findings: (1) 33% of migraine patients experienced spontaneous remission in the 8 years follow-up; (2) amplitudes of all CNV components decreased and habituation of the iCNV increased in the observed time; (3) the reduction of the iCNV amplitude was more pronounced in migraine patients who were in remission at T2 and in healthy subjects and less pronounced in both migraine groups with persisting headaches; (4) patients with worsened headache demonstrated the most pronounced loss of iCNV habituation at T1; (5) the iCNV amplitude at T2 differentiates patients with worsened migraine (larger iCNV amplitude) from patients with remission or healthy control subjects.
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