Article "Effects of continuous positive airway pressure on respiratory mechanics and breathing pattern in healthy individuals" (13th)

Clarisa Livia
16611022


The level of positive end-expiratory pressure (PEEP) is widely used during mechanical ventilation or during spontaneous breathing for acute or chronic lung disease. In this study, indirect breathing plethysmography (RIP) or death, electromyography (EMG) of transversus abdominis and skalene muscle and indirect calorimetry were used to achieve an integrated picture of respiratory system changes after exposure at 10 cmH2O CPAP levels.

In normal individuals, 10cm H2O CPAP induces acute overdistention. This overdistension activates the respiratory muscles of the accessory and improves the breathing work. Increased activity of inspired scalene muscle during CPAP explains the increase in RC contribution to tidal volume, whereas recruiting abdominal expulsion transversus may retain the lungs from overinflation by retracting the diaphragm toward the initial FRC position. We may assume that in patients with acute respiratory failure who do not tolerate different levels of CPAP, CPAP induces excessive distension and improves respiratory work.