33th Article " Mithocondria : much ado about nothing ? how dangerous is reactive oxygen species productive ?"

Nur fatmawati
16611047

Mithocondria : much ado about nothing ? how dangerous is reactive oxygen species productive ?

Reactive Oxygen Species (ROS) have long been known to be a component of the killing response of immune cells to microbial invasion. Recent evidence has shown that ROS play a key role as a messenger in normal cell signal transduction and cell cycling. These reactive molecules are formed by a number of different mechanisms and can be detected by various techniques. Here we briefly describe the biology behind some of these molecules and the means for their detectionReactive Oxygen Species (ROS) is a phrase used to describe a number of reactive molecules and free radicals derived from molecular oxygen. The production of oxygen based radicals is the bane to all aerobic species. These molecules, produced as byproducts during the mitochondrial electron transport of aerobic respiration or by oxidoreductase enzymes and metal catalyzed oxidation, have the potential to cause a number of deleterious events. The sequential reduction of oxygen through the addition of electrons leads to the formation of a number of ROS including: superoxide, hydrogen peroxide, hydroxyl radical,hydroxyl ion and nitric oxide.